Developing differentiated, best-in-class mAbs for immune-mediated diseases

Maximizing the power of mAbs

At Climb, we are focused on developing monoclonal antibodies that are optimized to meet the needs of patients living with serious, immune-mediated diseases. Our product candidates are crafted with intelligent designs that yield strong efficacy, excellent tolerability, and the flexibility to support extended dosing intervals that are customized per indication.

  • Focused on clinically validated B cell targets that have broad potential to provide the safe, effective, and durable knockdown of pathogenic cycles
  • Developing assets with high specificity and potency in mAb formats that are engineered for extended therapeutic windows
  • Exploring dose level and frequency to find the best solution for treating a wide variety of immune-mediated diseases

Lead Programs

Our lead programs are early clinical stage or clinic-ready, and our clinical development plan will
ensure we build the right therapy for the right indication.

Budoprutug, an anti-CD19 mAb

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CLYM116, Anti-APRIL Fc+, mAb

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